According to the Pan American Health Organization (PAHO), in the first 30 epidemiological weeks of 2019 in the Americas Region, there were 2,052,914 dengue cases (12,268 classified as severe), including 740 deaths. The number of cases reported is higher than the annual totals reported in the last two years (2017 and 2018). In 2018, there were 560,586 reported cases of dengue and 336 deaths. PAHO has warned that this latest cycle of dengue outbreak in the region is of particularly concern because children under the age of 15 are among the most affected. Additionally, the deadliest of the four serotypes of the virus, DEN-2 is the one currently affected children and adolescents. The ten countries most affected by dengue (highest incidence) are currently: Nicaragua, Brazil, Honduras, Belize, Colombia, El Salvador, Paraguay, Guatemala, Mexico and Venezuela.